Stationäre phasen mit SiN bindung für die flügkeitschromatographie

Abstract

 SiN bonded stationary phases for liquid chromatography The preparation of SiN bonded stationary phases for high-pressure liquid chromatography on the surface of silica with a specific surface area of 370 m 2/ g is described. The organic part of the stationary phase has a monomeric structure. In order to “modify” the selectivity to a required value, one or more functional groups, such as −COOH, −SO 3H, −NH 2, −CN or −NO 2, are introduced into the aliphatic chain. The spatial requirement of the organic “bristles” varies between 55 and 400 Å 2. Peak broadening, capacity ratios and mass transfer terms were determined in the linear velocity range 0.5–10 cm/sec with n-heptane, methanol and water as eluents. The change in the relative retention as a function of the eluent and of the functional groups is discussed.