State of the protein-synthesizing function of the placenta with premature rupture of membranes

Abstract

Zelynskyy O O, Domakova N V. State of the protein-synthesizing function of the placenta with premature rupture of membranes. Journal of Health Sciences. 2014;4(14):57-62. ISSN 1429-9623 / 2300-665X. http://journal.rsw.edu.pl/index.php/JHS/article/view/2014%3B4%2814%29%3A57-62 http://ojs.ukw.edu.pl/index.php/johs/article/view/2014%3B4%2814%29%3A57-62 https://pbn.nauka.gov.pl/works/510389 DOI: 10.5281/zenodo.13272 http://dx.doi.org/ 10.5281/zenodo.13272 The journal has had 5 points in Ministry of Science and Higher Education of Poland parametric evaluation. Part B item 1107. (17.12.2013). © The Author (s) 2014; This article is published with open access at Licensee Open Journal Systems of Radom University in Radom, Poland Open Access. This article is distributed under the terms of the Creative Commons Attribution Noncommercial License which permits any noncommercial use, distribution, and reproduction in any medium, provided the original author(s) and source are credited. This is an open access article licensed under the terms of the Creative Commons Attribution Non Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted, non commercial use, distribution and reproduction in any medium, provided the work is properly cited. This is an open access article licensed under the terms of the Creative Commons Attribution Non Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted, non commercial use, distribution and reproduction in any medium, provided the work is properly cited. Conflict of interest: None declared. Received: 15.11.2014. Revised 05.12.2014. Accepted: 08.12.2014. State of the protein-synthesizing function of the placenta with premature rupture of membranes Zelynskyy O O, Domakova N V Odessa State Medical University, Odessa A bstract State of the protein-synthesizing function of the placenta with premature rupture of membranes. Zelynskyy OO, Domakova NV Odessa State Medical University, Odessa The aim of the study was to evaluate protein-synthesizing function of the placenta in this category of patients. The research was performed during the 2005-2011 biennium. On the basis of specialized clinical maternity hospital number 5 (Odesa, Ukraine). A comprehensive prospective randomized clinical and laboratory examination of 217 pregnant women and their newborns. There were analyzed during pregnancy, childbirth and newborn status in pregnant women at term PROM 22-34 weeks of pregnancy. There was demonstrated that content TBG in serum of women and II group increased significantly compared with the control group at 32-38 weeks of pregnancy. High levels of TBG remained in the period 39-41 weeks, while at physiological indicators of current assessment AMGF, which is a marker of maternal part of the placenta in women II, III clinical and control groups showed that the most unfavorable for the prediction of perinatal pathology is increasing AMGF content like 32-38 weeks and 39-41 in week compared with the control group. The diagnostic and predictive values of the placenta proteins during PROM are discussed. Key words: premature rupture of membranes, placenta proteins, diagnosis, prognosis.