Abstract

(Bio)chemical sensors are one of the most exciting fields in analytical chemistry today. The development of these analytical devices simplifies and miniaturizes the whole analytical process. Although the initial expectation of the massive incorporation of sensors in routine analytical work has been truncated to some extent, in many other cases analytical methods based on sensor technology have solved important analytical problems. Many research groups are working in this field world-wide, reporting interesting results so far. Modestly, Spanish researchers have contributed to these recent developments. In this review, we summarize the more representative achievements carried out for these groups. They cover a wide variety of sensors, including optical, electrochemical, piezoelectric or electro-mechanical devices, used for laboratory or field analyses. The capabilities to be used in different applied areas are also critically discussed.

Highlights

  • The research and technology development ofsensors has clearly increased in the last few years due to the necessity of solving current problems in various fields in our society

  • An amperometric sensor based on mercaptopropionic acid (MPA) self-assembled monolayer (SAM) with horseradish peroxidase was immobilized by cross-linking with glutaraldehyde together with the mediator tetrathiafulvalene

  • The electrochemical response of those monolayers modified with inophores onto Ion selective Field Effect Transistors (ISFET) demonstrated the feasibility of this technology for sensor membrane fabrication and it opens further studies for other kind of devices such as optochemical sensors.This material modified with ionophores has applied in calcium and sodium determination [81]

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Summary

Introduction

The research and technology development of (bio)sensors has clearly increased in the last few years due to the necessity of solving current problems in various fields in our society. The analyte is physisorbed or chemisorbed onto the sensor in a reversible or irreversible process, which induces a response [6] In this respect, research activities in (bio)sensors must be focused to get reliable, accurate, portable, sensitive, and fast sensors, due to their ability to operate at lower-power, small-size and relatively low cost. Research activities in (bio)sensors must be focused to get reliable, accurate, portable, sensitive, and fast sensors, due to their ability to operate at lower-power, small-size and relatively low cost This objective is very ambitious and, for this reason, an interdisciplinary endeavor is clearly important to achieve it. These publications summarize the latest advances and future trends in producing, modifying, characterizing and integrating sensors. Lechuga - Optical sensor: SPR, microcantilevers http://www.cin2.es/biosensores

Maquieira
Nanomaterials and nanotechnologies
Carbon nanotubes
Noble metal nanoparticles
Quantum dots
Magnetic beads
Sensor nanofilms
Molecular imprinted polymers
Metal complexes
Organic ligands
Other materials
Electrochemical Sensors
Electronic tongues
Modified electrodes
Electrochemical flow-through sensors
Optical Sensors
Optical fibers
Optical flow injetion sensors
Surface plasmon resonance
Attenuated total reflection Fourier sensors
Slot-waveguide based refractometric sensors
Cantilever sensors
Commercial optical biosensors
Quartz crystal microbalance
Cantilever
Commercial Spanish Devices
Findings
Conclusions

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