State of Red Blood Indicators in Animals With Uranium Load

Abstract

Research relevance: the study of uranium load on the state of red blood is relevant in connection with the effect on the bone marrow and changes in it. Research objectives: to study conditions of red blood indicators in animals with a uranium load. Research materials and methods: experiments were carried out on rabbits of the chinchilla breed, weighing 1.7-2 kg. The animals were divided into 4 groups depending on the altitude above sea level and on the receipt of uranium from food. To obtain posthemorrhagic anemia, a single bloodletting was performed in the amount of 3% of the animal’s weight. Research results: in animals that were in mid-mountain conditions, stimulation of the red and white sprouts of the bone marrow and a pronounced regenerative reaction to the preliminary administration of uranium radionuclide and blood loss were observed. Conclusions: in animals kept in mid-mountain conditions near the uranium tailing dump, the regenerative potential of red and white bone marrow sprouts was reduced, which was confirmed by the absence of regenerative, regenerative processes after blood loss.