Abstract
Lens extract, when combined with staphylococcus toxin and injected intracutaneously, first sensitizes and then desensitizes the rabbit to lens extract. Injection of lens extract alone does not produce this effect. Because of this synergistic effect of the toxin on lens extract, a mixture of lens extract and staphylococcus toxin was used to treat two patients with intraocular inflammation associated with cutaneous sensitivity to lens extract. Both patients lost the cutaneous sensitivity to lens extract after treatment and it is probable, but has not been proved, that the ocular tissues were also desensitized. From the Wilmer Ophthalmological Institute, Johns Hopkins Hospital and University.
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