Abstract
THE phage-typing pattern of a strain of Staphylococcus aureus is believed to be determined by two factors: the ‘basic’ sensitivity of the strain to lysis by the typing phages, modified by interference exerted by the prophage or prophages it carries. The specificity of this interference may be narrow, and prevent lysis only by the phage carried by the strain and by closely related phages, or it may be very broad. Sometimes a single prophage will block the sensitivity to a number of apparently unrelated phages and have a profound effect on the phage-typing pattern1,2.
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