Abstract

Immunologic treatment of various dermatoses has been attempted in the past with varying success, and both specific and nonspecific biologic preparations have been employed. Because the use of a staphylococcus toxoid appeared rational in the treatment of furunculosis and other pyogenic dermatoses, we undertook to study the effect produced by such treatment in a series of patients in our private practice whose lesions were proving resistant to the ordinary therapeutic procedures. The study was begun with a staphylococcus toxoid prepared from multiple strains of toxin-producing staphylococci according to the technic of Dolman, 1 as described by Leonard and Holm. 2 Thirteen courses of treatment with this toxoid were included in this study. Later a preparation was used which combined the aforementioned type of staphylococcus toxoid with a bacterial antigen. 3 Only furunculosis and pustular acne vulgaris were treated at first, but later other miscellaneous dermatoses were included because we felt

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