Abstract
Indications for the initiation of venovenous extracorporeal membrane oxygenation (VV-ECMO) support have been adapted based on expert opinion and previous randomized clinical trials.1-5 In contrast, determining when VV-ECMO support may be discontinued safely remains unclear. Weaning strategies for VV-ECMO are not well-studied and primarily based on expert opinion, with wide variations across centers.6,7 Given the serious complications that may be seen with ECMO support and its association with high-resource use, identification of the safest and earliest timepoint to be decannulated from ECMO is of utmost importance.
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