Abstract
BackgroundWhile it is assumed that dialysis patients in Japan have a higher prevalence of atrial fibrillation (AF) than the general population, the magnitude of this difference is not known.MethodsStandardized prevalence ratios (SPRs) for AF in dialysis patients (n = 1510) were calculated compared to data from the general population (n = 26 454) living in the same area.ResultsThe prevalences of AF were 3.8% and 1.6% in dialysis patients and the general population, respectively. In male subjects, these respective values were 4.9% and 3.3%, and in female subjects they were 1.6% and 0.6%. The SPRs for AF were 2.53 (95% confidence interval [CI], 1.88–3.19) in all dialysis patients, 1.80 (95% CI, 1.30–2.29) in male dialysis patients, and 2.13 (95% CI, 0.66–3.61) in female dialysis patients.ConclusionsThe prevalence of AF in dialysis patients was twice that in the population-based controls. Since AF strongly contributes to a higher risk of cardiovascular mortality and morbidity in the general population, further longitudinal studies should be conducted regarding the risk of several outcomes attributable to AF among Japanese dialysis patients.
Highlights
Patients with end-stage renal disease (ESRD) have extremely high mortality rates, and the leading cause of death among ESRD patients is cardiovascular disease.[1]
Age-adjusted mean levels of systolic blood pressure (SBP) and High-sensitivity Creactive protein (hsCRP) in dialysis patients were higher than the mean levels in community dwellers
We found that 3.8% of Japanese dialysis patients had atrial fibrillation (AF) and that the prevalence in dialysis patients was twice that in community dwellers living in the same area based on surveys conducted in 2003 to 2007
Summary
Patients with end-stage renal disease (ESRD) have extremely high mortality rates, and the leading cause of death among ESRD patients is cardiovascular disease.[1]. We should establish preventive measures for improving the prognosis of Japanese dialysis patients with AF using epidemiological evidence based on this specific population. Methods: Standardized prevalence ratios (SPRs) for AF in dialysis patients (n = 1510) were calculated compared to data from the general population (n = 26 454) living in the same area. Results: The prevalences of AF were 3.8% and 1.6% in dialysis patients and the general population, respectively In male subjects, these respective values were 4.9% and 3.3%, and in female subjects they were 1.6% and 0.6%. Since AF strongly contributes to a higher risk of cardiovascular mortality and morbidity in the general population, further longitudinal studies should be conducted regarding the risk of several outcomes attributable to AF among Japanese dialysis patients
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