Abstract
A 52 year old female suffering from severe progressive multiple sclerosis was administered quantifiable amounts of standardized cannabis and monitored over the period of one year, while providing daily pain charts and records of her condition. An average daily intake of 500 mg of Tetrahydrocannabinol as cannabis was required to achieve a desired quality of life.
Highlights
Multiple Sclerosis (MS) is a difficult disease both to diagnose and to treat
Her caregiver provided daily pain charts, plus ingested medications, and a description of the subject's general well being throughout the study
Mobile phase at 1 ml/ min was isocratic with 14% aqueous (1:25:974 phosphoric acid: acetonitrile: distilled water) and 86% organic phase
Summary
Multiple Sclerosis (MS) is a difficult disease both to diagnose and to treat. Diagnosis often requires multiple visits to the physician and it may take years before MS is diagnosed, typed and treated. Many types of medications including anticholinergics, antispasmodics, benzodiazepines and opiates are used to manage the muscle spasms, bladder incontinence issues and nerve pain that may be associated with MS They do prevent recurrence and slow progression of the illness. Intermittent ACTH treatment occurred until 1985 when Magnetic Resonance Imaging confirmed her diagnosis with MS She began daily injections of Copaxone, which gave benefits including reduction of muscle spasms and a degree of pain management. For the following year she ingested cannabis that had been tested for concentrations of the most abundant cannabinoids including Delta-9 Tetrahydrocannabinol (THC), Cannabidiol (CBD) and Cannabinol (CBN) Her caregiver provided daily (email) pain charts, plus ingested medications, and a description of the subject's general well being throughout the study
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