Abstract

Much neurobiological and psychological knowledge about brain development and maturation in pregnancy and early childhood should be evaluated simultaneously, due to several underlying pathophysiological findings, because with proven clinical evidence, with time greater than twenty years, such as situations of Adverse Emotions in Childhood (ACE ), Post Traumatic Stress Disorder (PTSD), and recently the absence/deficit of oxytoninergic neurons responsible for family synchrony, cause a series of aberrant pathophysiological effects, with inflammatory, behavioral, cognitive, affective and social impairments [1].

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