Abstract
In the present work, the novel stainless-steel grade 304 QDs was synthesized by laser ablation in water to treat Laryngeal carcinoma in vitro, for the first time without an external laser source or magnet for hyperthermia. The characterizations of QDs include absorption, morphology, quantitative analysis by atomic absorption spectrometer, and phase identification. Characterizations of QDs reveal that QDs possess resonance fluorescence property at NIR band and the valence of Chromium (Cr) is + 3. Adding 10 µL of a diluted solution of QDs to the cell culture medium suppresses both cell proliferation & VEGF gene expression significantly, indicating the death of cancer cells. Both the low percentage of QDs and the valence of Cr exclude the toxicity of QDs. The experimental results support to the moment that the most apparent mechanism for cancer death is the heat shock due to NIR resonance fluorescence property of QDs. Also, QDs have the ability to absorb the required energy for excitation from the surrounding environment.
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