Abstract

The destruction of cyanocobalamin in liquid multiple vitamin preparations can be greatly reduced by the addition of small amounts of complex cyanides or iron salts. Cyanocobalamin stabilization with iron salts is not as effective as 'with complex cyanides under conditions designed to exclude air. The superiority of complex cyanides over iron salts was also demonstrated in partly filled containers where a large volume of air overlaid the product. The complex cyanides were also effective in reducing the destruction of cyanocobalamin induced by ultraviolet irradiation. The destruction of cyanocobalamin in liquid multiple vitamin preparations can be greatly reduced by the addition of small amounts of complex cyanides or iron salts. Cyanocobalamin stabilization with iron salts is not as effective as 'with complex cyanides under conditions designed to exclude air. The superiority of complex cyanides over iron salts was also demonstrated in partly filled containers where a large volume of air overlaid the product. The complex cyanides were also effective in reducing the destruction of cyanocobalamin induced by ultraviolet irradiation.

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