Abstract

An atomic force microscope makes imaging of biological molecules possible at high resolution. To this end all samples have to be fixed securely to a flat solid support so that they cannot be displaced by the scanning tip. We herein describe a new method to fix the biological samples to glass surfaces by depositing a thin layer of plasma polymerized methane gas in a high vacuum chamber. Such samples can thus be imaged repeatedly by an atomic force microscope without any loss of image quality.

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