Abstract
SummaryHeating unfractionated, sterile human serum for 36 or 72 h at 45 or 50 C, unlike heating immune serum globulin (human), failed to diminish the fragmentation of immunoglobulin G during subsequent storage. Over the range –22 to 37 °C, degradation as assessed by immunoelectrophoresis was a strong function of storage temperature; it was somewhat enhanced by prior heating
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