Abstract
Thermal stabilities of the hairpin structure of (CCG)4 trinucleotide repeats were examined in a bulk aqueous solution and inside amine-functionalized silica mesopores (pore diameters: 3.5 and 5.7 nm). The results confirmed that the denaturation temperatures of (CCG)4 hairpin within TMAP-MPSs were about 10 °C lower than those in bulk water. On the basis of enthalpy–entropy compensation, enthalpy change upon denaturation (ΔH) inside the pore was estimated to be 0.8 kcal mol−1 lower than that for the bulk system.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
