Abstract
As a part of studies on the possible application of pluronic F-127 gels for drug delivery systems, an investigation was carried out to characterize cefazolin stability in aqueous pluronic F-127 gels. Pseudo-first-order rate constants for the cefazolin degradation were obtained from different concentrations of pluronic F-127 gels at temperatures of 35°, 45°, and 55°C. Rate measurements were also carried out in the gels composed of different pluronic F-127 concentrations (20%, 25%, and 30% w/v).
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