Abstract

Objectives We studied the stability of 33 analytes related to clinical chemistry, bone, and vitamin metabolism, after storage in serum separator tubes (SST™). Design and methods Blood was collected from 6 subjects using SST tubes. Some serum remained in the tube in contact with the barrier gel and was stored at − 80 °C for 12 mo. Results Clinically significant changes occurred only in 1,25-dihydroxyvitamin D and retinol-binding protein. Conclusions Freezing SST tubes before sample analysis is a viable option for some analytes.

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