Abstract
The stability of 11-Nor-9-delta-tetrahydrocannabinol-9-carboxylic acid (THCCOOH) from urine specimens stored in polypropylene (PP), polyethylene (PE) and polystyrene (PS) containers was examined. Urinesamples containing 100μg/m L TI-ICCOOH were stored at -20°C, 4°C and 25°C up to 180 days. The samples were analyzed at 0,5, 10, 20, 30, 60, 90, 105, 135, 150 and 180 days, and alteration of the analyte pattern during storage were determined by a validated liquid chromatography-tandem mass (LC-MS/MS). The concentration of THCCOOH significantly decreased to approximately 20% of its initial concentration within 5 days in all three containers at all temperature conditions. All loses of THCCOOH were relatively stabilized after 5 days. The results indicated that THCCOOH was preferred to store in PP and PE containers at 4 °C.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
