Stability Monomolecular Properties of Archaeal Tetraether Lipids Layers onto Solid Substrates

Sri Vidawati,Udo Bakowsky

doi:10.4236/abc.2022.121003

Abstract

This paper reports the recent findings related to the stability properties of tetraether lipid layers. Organizations moleculars of chemical structure modified of Langmuir-Blodgett layers of archael tetraether lipids from the archebacterium Sulfolobus acidocaldarius on the wafer silicon substrates are investigated stable and organized. The behavior of Langmuir-Blodgett layers of chemical structure modified of archaeal tetraether lipids on the wafer silicon substrates is characterization using Differential Scanning Calorimetry (DSC) and Atomic Force Microscopy (AFM). The thermodynamics behavior and stability of Langmuir-Blodgett layers of archael tetraether lipids on the wafer silicon substrates are shown. Stability of the lipid membranes is of great importance to a number of biomedical applications, including intravenous drug delivery, biomaterials, and biosensors.

Highlights

Lipid membranes supported on solid substrates are considered as an important model to mimic the natural cell membranes in fundamental studies [1]
This paper reports the recent findings related to the behaviour and the stability of chemical modified structure of Langmuir-Blodgett film tetraether lipid at the air-water interfaces on the wafer silicon substrates, with special attention to the calorimetry studies which would be in line with the assumption that the archael tetraether lipids membrane has significant influence on lipid conformation, membrane thickness organization, and headgroup orientation
Long term stability of the tetraether lipids film can be derived from Figure 2, at 19 ̊C, pH 5.5 compression-decompression surface pressure/area isotherms for caldarchaeol-CyCl, GDNT, caldarchaeol-PO4

Summary

Introduction

Lipid membranes supported on solid substrates are considered as an important model to mimic the natural cell membranes in fundamental studies [1]. Vidawati et al [12] [13] [14] were shown that stability organization molecular of Langmuir-Blodgett films chemically modified structure of archaeal tetraetherlipids. It could be shown that in the monomolecular Langmuir-Blodgett film of chemically modified structure of archaeal tetraether lipids at the air-water interface molecules on the wafer silicon substrate is oriented upright standing and the horseshoe-like orientation [15] [16]. This paper reports the recent findings related to the behaviour and the stability of chemical modified structure of Langmuir-Blodgett film tetraether lipid at the air-water interfaces on the wafer silicon substrates, with special attention to the calorimetry studies which would be in line with the assumption that the archael tetraether lipids membrane has significant influence on lipid conformation, membrane thickness organization, and headgroup orientation

Lipid and Other Materials

Silicon Wafers Subtrates

Langmuir Blodgett Monolayer Experiments

Atomic Force Microscopy Measurements

Result and Discussion