Abstract
Aims: The present study aimed to investigate the desirable loading time of micro-screw implant by stability evaluation and detecting the possibility of using alendronate sodium to increase the stability. Materials and methods: Forty eight micro-screw implant, twelve adult rabbits and fourteen alendro- nate sodium ampoules were used in this study, the rabbits were divided into two main groups, treated and control group, which further subdivided into three subgroups. Eight micro-screw implant instilled in tibiaes of each subgroup just six of them used for test the remaining cancelled, the stability test down using the periotest. These subgroups were nominated according to the loading times which are immedi- ate loading, loading after two weeks and loading after four weeks with stability measured after instilla- tion, before and after loading and two weeks after loading. Results: No significant differences between subgroups before loading and after two weeks of loading but significant after loading. For immediately loaded treated subgroup no significant differences between immediate loading and two weeks after loading. For two and four weeks treated subgroup a significant difference in stability between immedi- ate instillation and after loading. Conclusions: Micro-screw implant even smaller diameter could be used as a fixed anchorage in orthodontics and possibly could be loaded safely from time of immediate instillation, further the use of alendronate sodium add no benefit to increase stability according to the criteria used in this study.
Highlights
Good anchorage control is one of the prerequisites of successful orthodontic therapy
The stability is of two components: Primary stability which is established from the mechanical lock between the micro-screw implant surface and bone.[5]. It is depends on the thickness and integrity of the cortical bone
All micro-screws and rabbits were divided into two groups; the first untreated group is the plane group (p) which further subdivided into three subgroups, which are, the immediate loading plane subgroup (0WP), 2-week healing plane subgroup (2WP) and 4-week healing plane subgroup (4WP) while the second group is the treated group (T) which subdivided into three subgroups, the immediate load treated subgroup(0WT), 2week healing treated subgroup (2WT) and 4 week treated subgroup (4WT)
Summary
Good anchorage control is one of the prerequisites of successful orthodontic therapy. Micro-screw implant have been proven to be useful in establishing absolute anchorage without the use of extra-oral appliances, add to their flexibility in choosing implant locations, lower medical costs, simpler implant surgery, and lower degrees of discomfort after implantation compared with traditional dental implants.[1,2] these miniscrews loosen and their failure rate may be as high as 25%. The stability is of two components: Primary stability which is established from the mechanical lock between the micro-screw implant surface and bone.[5] It is depends on the thickness and integrity of the cortical bone. [15] There are no studies comparing the effect of systemic administration of alendronate on dental implant osseointegration. A rabbit tibia model was used to examine the effects of alendronate as osteoclast inhibitors at different loading and healing times on mechanical stability. The present study aimed to investigate the desirable loading time of micro-screws by stability evaluation
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