Stabil Koroner Arter Hastalığı Olan Hastalarda Bazal T-Dalgası Pik-Son İntervali ile Kalp Atış Hızı Düzelme İndeksi Arasındaki İlişki

Abstract

OBJECTIVES: Autonomic dysfunction is detected in patients with coronary artery disease and is indicative of poor prognosis. The aim of this study was to compare baseline T peak-end interval (Tp-e) and heart rate recovery index [HRR-I] values in patients with stable coronary artery disease who had a left ventricular ejection fraction [EF] > 50 % and 50 %, had 3-vessel diseases on coronary angiography. Baseline Tp-e and heart rate values of both groups were measured and transthoracic echocardiograms were performed at the beginning. Both Group 1 and 2 were then subjected to exercise testing according to the Bruce protocol and heart rates were measured at the peak and 1st, 2nd, and 3rd minutes of exercise. RESULTS: There was a statistically significant difference between group 1 [95.8 ± 6.8 msec] and group 2 [71.4 ± 5.1 msec] with regard to basal Tp-e [P<0.0001]. There was a significant difference between group 1 [108.1±7.9] and group 2 [79.3±7.7] in terms of corrected Tp-e(cTp-e) values [P<0.0001]. Looking at HRR-I at the 1st-minute recovery phase [14.4 ± 2.1 vs 20.1 ± 3.5], when looking at HRR-I at the 2nd-minute recovery phase [26.3 ± 2.2 vs 45.1 ± 2.4], when looking at HRR-I at the 3rd-minute recovery phase [42.6 ± 2.9 vs 64.1 ± 2.6], there was a statistically significant difference between the groups [P<0.00001]. CONCLUSION: Autonomic delaying is more prominent, the Tp-e interval value was higher and HRR-I values were lower in patients with stable angina with EF < 50%.