Abstract
The safety and efficacy of selective serotonin reuptake inhibitors (SSRIs) in adolescents is a topic of great import, complexity, and controversy. Conflicting evidence derived from clinical trials, translational research, and basic science demands that investigators in the field use critical thinking in the synthesis of evidence from varying sources. The new study by Ricci and Melloni presented in the current issue of this journal shows that exposure to low-dose fluoxetine during adolescence predisposes Syrian hamsters to offensive aggression, with demonstrable neurophysiologic changes. This work adds to the understanding of the mammalian neuropathways of aggression, but is limited in its direct generalizability to human adolescent clinical populations.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
