Abstract
Using swept-source optical coherence tomography/angiography (SSOCT/A), we present a non-invasive examination of the zebrafish brain to comprehend the vasculature and altering cellular dynamics in the cerebral stroke model. Reduced or blocked blood flow to the brain during an ischemic stroke eventually results in cell death from a lack of oxygen and nutrients. SSOCT is used to examine ischemic stroke's aberrant/anomalous blood flow features using phase variance and the Doppler method. The SSOCT speckle-contrast technique is used to track the ensuing cell demise. Fast acquisition times, reduced motion artefacts, label-free viewing, and non-invasive testing are all features of the SSOCT approach for disease surveillance.
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