Abstract
Super-resolution microscopy and single molecule fluorescence spectroscopy require complementary and mutually exclusive experimental strategies that optimize either spatial or temporal resolution, making their combined implementation a challenge. With a GPU-driven, camera-based measurement strategy we demonstrate that it is possible to achieve this in ∼5 minutes (including measurement time) using the epidermal growth factor receptor (EGFR) as our model. EGFR, a transmembrane receptor tyrosine kinase, is a crucial regulator of proliferation and survival, and its mutations and dysregulated signalling have been implicated in many cancers.
Full Text 
Sign-in/Register to access full text options
Sign-in/Register to access full text options 
Published version (
Free)
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
