Abstract

Recent breakthroughs in fluorescence microscopy are producing notable improvements in imaging resolution.[ 1 ] These ongoing technical advances should have a major positive impact on the emerging field of cell imaging using single molecule methods, and help merge the sub-disciplines of cell and molecular biology.[2] However, the full potential of many of these new high-resolution imaging methods will only be achieved if they employ extremely bright and highly stable luminescent probes that do not undergo photobleaching or photoblinking.

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