SQUAMOUS ODONTOGENIC TUMOR: REPORT OF A RARE CASE

Abstract

A 51-year-old black woman sought care in a hospital because of an asymptomatic lesion involving the left anteroposterior region of the mandible identified in a routine panoramic radiograph. Intraoral physical examination revealed a small expansion of the region. Radiographic examination showed a multilocular radiolucent lesion with well-defined borders in the left side of the mandible, involving elements 31 to 35 and measuring approximately 5 cm in diameter. The treatment consisted of an excisional biopsy complemented with curettage. Histopathologic examination showed fragments of a benign odontogenic neoplasia presenting proliferation of polyhedral and cuboidal epithelial cells with eosinophilic cytoplasm, organized in nests, and intermingled by dense connective tissue. Cystic degeneration and individual keratinization of neoplastic cells were also observed. Neoplastic cells were positive in immunohistochemical reactions for cytokeratins 14 (CK14) and 19 (CK19). A diagnosis of squamous odontogenic tumor was established, and the patient remains without signs of recurrence after 18 months. A 51-year-old black woman sought care in a hospital because of an asymptomatic lesion involving the left anteroposterior region of the mandible identified in a routine panoramic radiograph. Intraoral physical examination revealed a small expansion of the region. Radiographic examination showed a multilocular radiolucent lesion with well-defined borders in the left side of the mandible, involving elements 31 to 35 and measuring approximately 5 cm in diameter. The treatment consisted of an excisional biopsy complemented with curettage. Histopathologic examination showed fragments of a benign odontogenic neoplasia presenting proliferation of polyhedral and cuboidal epithelial cells with eosinophilic cytoplasm, organized in nests, and intermingled by dense connective tissue. Cystic degeneration and individual keratinization of neoplastic cells were also observed. Neoplastic cells were positive in immunohistochemical reactions for cytokeratins 14 (CK14) and 19 (CK19). A diagnosis of squamous odontogenic tumor was established, and the patient remains without signs of recurrence after 18 months.