Abstract

Primary squamous cell carcinoma (SCC) of the kidney is an extremely rare entity representing only 0.5-15% of all urothelial cancers. Herein, we reported a rare case of renal cell carcinoma with SCC extended to the pelvis. A 56 year-old female patient referred to the oncology clinic with complaints of pain in the right flank. The CT showed a hypodense renal mass of size approximately 2 × 2.1 cm in the upper pole of the right kidney. High grade urothelial carcinoma and squamous cell carcinoma extended to renal capsule, but not pass to perirenal fat. Vascular invasion was present, but perineural invasion was not seen. Ureteral margin was free of tumor. Biopsy showed one hilar lymph node involved with tumor in the near right kidney. A few slightly stones smaller than normal 0.4 × 0.9 cm can be seen in the calyx of the asymptomatic hydronephrosis of left kidney. SCC is one of the rare histological tissues in the kidney and hydronephrosis is the most common complaints in more patients with this malignancy.

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