Abstract
Aim: To retrospectively study 26 patients with squamous cell carcinoma (SCC) of the ocular surface to determine pathological and clinical characteristics of tumour associated with outcome. Methods: Patients with conjunctival...
Highlights
MATERIALS AND METHODS All cases diagnosed as squamous cell carcinoma of the conjunctiva or cornea from March 1994 to the end of December 2000 were obtained from the records of the Department of Anatomical Pathology, St Vincent’s Hospital, which receives histopathology specimens from the Royal Victorian Eye and Ear Hospital
Histological evidence of solar injury, which is recognised as a major risk factor for conjunctival squamous cell carcinoma (SCC), was found in all of our cases, compared with only 50% found by Tabrizi and colleagues in a similar Australian population.[5]
Conjunctival SCC has been associated with human papillomavirus (HPV) infection, especially genotype 16.5 12 As a previous study of a similar group of patients from the same institution, but from an earlier period (1980–92) demonstrated an incidence of 57% of HPV, including genotypes 6/11, 16, and 18 in conjunctival SCC,[5] we did not repeat these investigations in our cohort
Summary
To retrospectively study 26 patients with squamous cell carcinoma (SCC) of the ocular surface to determine pathological and clinical characteristics of tumour associated with outcome
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