Abstract
Squamous cell carcinoma (SCC) of kidney is a rare entity. It behaves aggressively in case of kidney. It is usually diagnosed at an advance stage associated with poor outcome. Renal squamous cell carcinoma is usually associated with stones. Chronic irritation due to stone cause metaplasia of lining epithelium resulting in transformation of squamous cell carcinoma which is rare but the most fatal complication. Here we are presenting a case of renal squamous cell carcinoma associated with stones.
Highlights
Squamous cell carcinoma is a very rare tumour which makes up under 1% of all malignant tumours of kidney
Risk factors leading to renal squamous cell carcinoma include renal calculi, infection, endogenous and exogenous chemicals, vitamin A deficiency, hormonal imbalance, and radiotherapy[2]
Few glomeruli and tubules were observed at the periphery intermixed with neoplastic lesions as showed in the photomicrograph 2 and 3
Summary
Squamous cell carcinoma is a very rare tumour which makes up under 1% of all malignant tumours of kidney. This tumour is very aggressive in nature and prognosis is poor because it is usually diagnosed in advance stage[1]. Ultrasound kidney showed kidney with features of hydronephrosis and multiple renal stones. Photograph 1: The gross examination of received sample exhibiting fragments of kidney with solid to cystic areas. Photograph 2: The histopathological image showing with an invasive squamous cell carcinoma on the right side of this field distorting the renal architecture with a single glomerulus of the left side of the field is identified. Salma Parween and Sadaf Razzaq carried out the literature search
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