Abstract
Squamous cell carcinoma (SCC) is the most common oral malignancy and frequently occurs on the lateral edge of the tongue. However, when related to other sites such as the gingiva, it is painless and occurs mainly in the posterior mandible. A 78-year-old female patient sought dental care for mass growth, bleeding on chewing, and maxillary pain. Medical history revealed a treated breast cancer and a shoulder lipoma. An intraoral clinical examination showed an exophytic-ulcerated, bleeding, and painful lesion located on the right maxillary alveolar ridge. On radiographic examination, an osteolytic radiolucent area appeared. The clinical diagnosis was suggestive of SCC. An incisional biopsy was performed, and the histopathologic examination revealed epithelial proliferation of papillomatous aspect, hyperchromatic cells, abundant mitosis, evident hyperplasia of the basal layer, individual keratinization and acantholic areas, in addition to numerous keratin pearls, confirming the diagnosis of SCC. The patient died before maxillectomy.
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