Abstract
ABSTRACTObjectives:To report a case series of squamous cell carcinoma (SCC) in the foot, describing previous risk factors, surgical treatment, histopathological findings, and functional and oncological results. Methods:Nine consecutive patients diagnosed with SCC of the foot were treated at a single institution and prospectively analyzed for risk factors related to the disease, surgical outcome, and histopathological, functional and oncological results. All patients had identifiable risk factors for SCC. Results:Definitive treatment consisted of partial (6 patients) or total (3 patients) amputation of the foot. The functional score was good or excellent in the surviving patients. Early identifiable risk factors are present in most patients. Biopsy when this diagnosis is suspected, in association with oncological principles, avoids diagnostic and treatment errors. Conclusion:Despite delayed diagnosis and surgical treatment with partial and total amputations of the foot in our series, we observed good oncological outcomes that avoided systemic spread of the disease and achieved expected functional results. Level of Evidence V; Case series.
Highlights
Squamous cell carcinoma (SCC) is a rare condition in the foot.[1,2] The disease was first described in 1828 by Marjolin, and its malignancy was recognized by Dupuytren.[3,4] squamous cell carcinoma (SCC) originates in keratinocytes and may develop a precursor lesion or de novo lesions.[4]
Nine consecutive patients diagnosed with SCC of the foot were treated at a single institution and prospectively analyzed for risk factors related to the disease, surgical outcome, and histopathological, functional and oncological results
Reports in the literature state that 13% occur in the legs, and this is the most common primary cancer of soft tissue in the foot, with an incidence slightly greater than melanoma and synovial sarcoma.[6]
Summary
Squamous cell carcinoma (SCC) is a rare condition in the foot.[1,2] The disease was first described in 1828 by Marjolin, and its malignancy was recognized by Dupuytren.[3,4] SCC originates in keratinocytes and may develop a precursor lesion or de novo lesions.[4]. Reports in the literature state that 13% occur in the legs, and this is the most common primary cancer of soft tissue in the foot, with an incidence slightly greater than melanoma and synovial sarcoma.[6]
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