Squamous cell carcinoma in situ of the endometrial cavity

Abstract

1. Squamous cell carcinoma in situ was discovered in the uterus of a patient three and a half years after apparent successful radiation treatment of Stage II squamous cell carcinoma of the cervix.2. The uterus was also affected by multiple myomas and pyometra, the latter due to cervical atresia.3. Neither the operating surgeon nor the pathologist anticipated encountering the condition, and neither took the steps necessary for complete diagnosis or treatment.4. Either one of two mechanisms which produce carcinoma in situ of the endometrial cavity could have been operative in this patient: surface spread from disease in the cervix, or malignant transformation of squamous metaplasia of the endometrium. The first method was considered more likely here.