Abstract
Cancers of the kidney account for 2% of all the total human cancer. Squamous cell carcinoma (SCC) of renal pelvis is a rare neoplasm, accounting for only 0.5 to 0.8% of malignant renal tumors. In most cases, renal SCC is associated with chronic infections, chronic renal calculi, radiotherapy or any factor that can irritate the urothelium. We report a female patient aged 60 years diagnosed with Right Non-functioning Kidney with Nephrolithiasis with Suspicious Mass. Histopathological diagnosis with Squamous Cell Carcinoma in Stage III with Staghorn Calculi. In long standing urolithiasis, possibility of concomitant harboring of malignancy needs to be taken into consideration.
Highlights
Squamous cell carcinoma (SCC) of the renal pelvis is a rare neoplasm, accounting for only 0.5 to 0.8% of malignant renal tumors.4, 5Although the incidence of this tumor in the kidney, is rare, whenever a renal mass is accompanied by a longstanding renal stone, and this differential diagnosis should be considered.[6]
We report a case of a 60 years old female patient in 2019 AD, she complained of chronic dull aching abdominal pain which was diagnosed as Right Non-functioning Kidney with Nephrolithiasis with suspicious mass after clinico-radiological evaluation
Squamous Cell Carcinoma, Well Differentiated type was seen along with renal pelvis dysplasia and tumor extending through the perinephric fat
Summary
Cancers of the kidney account for 2% of all the total human cancer.[1, 2] Kidney cancer is the ninth most common cancer in men and 14th most common in women worldwide.[3]Squamous cell carcinoma (SCC) of the renal pelvis is a rare neoplasm, accounting for only 0.5 to 0.8% of malignant renal tumors.4, 5Although the incidence of this tumor in the kidney, is rare, whenever a renal mass is accompanied by a longstanding renal stone, and this differential diagnosis should be considered.[6]In most cases, renal SCC is associated with chronic infections, chronic renal calculi, radiotherapy, or any factor that can irritate the urothelium.[7, 8] Other potential causes have been described in the literature, including tuberculosis, immunosuppression with azathioprine, analgesic abuse with phenacetin, radiation therapy and chronic rejection in a transplant kidney.[7, 9, 10]We report a case of a 60 years old female patient in 2019 AD, she complained of chronic dull aching abdominal pain which was diagnosed as Right Non-functioning Kidney with Nephrolithiasis with suspicious mass after clinico-radiological evaluation. Squamous cell carcinoma (SCC) of the renal pelvis is a rare neoplasm, accounting for only 0.5 to 0.8% of malignant renal tumors.4, 5Although the incidence of this tumor in the kidney, is rare, whenever a renal mass is accompanied by a longstanding renal stone, and this differential diagnosis should be considered.[6] Renal SCC is associated with chronic infections, chronic renal calculi, radiotherapy, or any factor that can irritate the urothelium.[7, 8]
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