Squamous cell carcinoma in a central bearded dragon

Abstract

A four-year-old, female central bearded dragon (Pogona vitticeps) was presented for evaluation of an ulcerated mass involving the left eyelid. Biopsies of the eyelid were performed and submitted for histopathology. Histopathology revealed a squamous cell carcinoma. Previous publications have described 12 cases of squamous cell carcinomas in bearded dragons, with nine located in the eyelids or periocular tissues. Imiquimod 5% cream (Aldara) is a novel immune response modifier that has been reported as a successful treatment for Bowen's disease in humans, and as a treatment option in cats with multicentric squamous cell carcinomas. In this case study, imiquimod 5% cream was applied to the lesion and clinical findings noted. Initial findings demonstrated a clinical response to imiquimod 5% cream, with a decrease in inflammation, tumour regression and the opening of the eyelids. A relapse occurred after 75 days with sudden deterioration, inflammation, closure of the eyelids and infection.