Abstract

Squamous cell carcinoma is the most common oral malignant neoplasm, occurring mainly in individuals over 45 years old. A 16-year-old girl sought dental care, complaining of a tongue wound and reporting frequent trauma at the site. A prior diagnosis of acute lymphoid leukemia at the age of 6 years, treated with chemotherapy, was reported. On intraoral examination, an ulcerated lesion was observed at the left border of the tongue, with an irregular shape and high, hardened edges, measuring 5 mm. An incisional biopsy was performed and the histopathologic analysis confirmed an oral squamous cell carcinoma. Additional immunohistochemistry tests for p16 were performed, showing negative result, and magnetic resonance imaging confirmed the expansive infiltrative lesion without cervical lymph nodes. The patient was submitted to partial glossectomy without neck dissection. After 2 months, the patient remains with no signs of lesion recurrence.

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