Abstract
Background: Keloids may follow local skin trauma or inflammation leading to pruritus, pain, restriction of movement or cosmetic disfigurement. Objectives: To compare between the efficacy and tolerability of spray versus intralesional cryotherapy for keloids. Patients and methods: Fifty patients with keloids were randomized to treatment with spray cryotherapy (group I) or intralesional cryotherapy (group II). Swada and Sone scoring of scars was performed at treatment and follow-up (6 months). Histopathological examination was done before and after end of treatment sessions. Results: Intralesional cryotherapy showed greater efficacy than spray cryotherapy. Fewer treatments were required with intralesional cryotherapy than with spray cryotherapy. Conclusion: Intralesional cryotherapy was more effective and tolerable modality for treatment of keloids than spray technique with greater internal freezing area.
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