Abstract
Resveratrol is an antioxidant abundant in red fruits, and one of the most powerful inhibiting reactive oxygen species (ROS) and oxidative stress (OS) produced by human metabolism. The effect of the spray drying processing conditions of blueberry juice (BJ) and maltodextrin (MX) mixtures was studied on content and retention of resveratrol. Quantitatively, analysis of variance (ANOVA) showed that concentration of MX was the main variable influencing content of resveratrol. Response surface plots (RSP) confirmed the application limits of maltodextrins based on their molecular weight, where low molecular weight MXs showed a better performance as carrying agents. After qualitatively comparing results for resveratrol against those reported for a larger antioxidant molecule (quercetin 3-D-galactoside), it was observed a higher influence of the number of active sites available for the chemical interactions, instead of stearic hindrance effects.
Highlights
Human metabolism continuously produces reactive oxygen species (ROS) by normal respiration and cellular functions
The effect of processing conditions in spray drying of blueberry juice and maltodextrin mixtures (BJ-MX) on content and retention of resveratrol was studied
Analysis of variance (ANOVA) showed that concentration (C) was the main variable influencing the content of resveratrol
Summary
Human metabolism continuously produces reactive oxygen species (ROS) by normal respiration and cellular functions. These species may cause cellular damage by affecting the DNA, stimulating free radical chain reactions, and provoking more than one hundred diseases [1]. An over production of oxidative species and a weak immune system, may result in an imbalance in the body, developing oxidative stress (OS) This OS can generate changes in cell volume, and make other biomolecules (i.e., proteins, lipids and nucleic acids) to malfunction, leading to other major degenerative diseases such as cancer, diabetes, atherosclerosis, stroke, asthma, arthritis, dermatitis and aging, among others [3]. There are various types of antioxidants in nature, among them are found flavonoids and stilbenoids structures such as quercetin 3-D-galactoside, resveratrol, myricetin and Antioxidants 2019, 8, 437; doi:10.3390/antiox8100437 www.mdpi.com/journal/antioxidants
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