Abstract
We present evidence for a case of spotted fever rickettsiosis with severe complications in a young adult male. Although spotted fever group rickettsiae (SFGR) have been reported as the most prevalent cause of rickettsiosis in rural areas of Sabah, Malaysia since the 1980s, this is the first detailed case report of suspected SFGR in the state. Current data on the prevalence, type, and thorough clinical reports on complications of SFGR and other rickettsioses in Sabah is lacking and required to raise the awareness of such diseases. There is a need to emphasize the screening of rickettsioses to medical personnel and to encourage the use of appropriate antibiotics as early treatment for nonspecific febrile illnesses in this region. Suspected rickettsioses need to be considered as one of the differential diagnoses for patients presenting with acute febrile illness for laboratory investigations, and early treatment instituted.
Highlights
Over the past 25 years, there has been an increase in the knowledge of rickettsial pathogens worldwide [1]
2000s [13,14], cross-sectional surveyrickettsioses in 1986 [17], in and prospective study. In this evidence for aone case of spotted fever a one wildlife researcher ininSabah, Malaysia, report, we present evidence for a case of spotted fever rickettsioses in a wildlife researcher in
Based on on the the available available evidence evidence of of response response to todoxycycline doxycycline and and azithromycin azithromycin therapy therapy and and on on Based the seropositivity demonstrated via spotted fever group rickettsiae (SFGR), there is evidence suggestive of the seropositivity demonstrated via immunofluorescence assay (IFA) and western blot (WB) tests against SFGR, there is evidence suggestive of SFG rickettsiosis in this patient
Summary
Over the past 25 years, there has been an increase in the knowledge of rickettsial pathogens worldwide [1]. Reports of areas though current data on the prevalence and type of rickettsioses are scarce [12,13,14,15,16]. This disease in Sabah are limited to two retrospective serological studies in the early 2000s [13,14], one Reports of thissurvey disease. Sabah, highlighting the need for increased awareness of rickettsioses as a cause of acute febrile illness in this. Malaysia, highlighting the need for increased awareness of rickettsioses as a cause of acute febrile region
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