Abstract

Polymorphisms in TNFRSF1A , the gene encoding tumor necrosis factor receptor 1, increase the risk for multiple sclerosis (MS). Two TNFRSF1A polymorphisms were investigated in MS, and they modulated disease severity (rs4149584) and had functional consequences in the receptor (rs1800693 and rs4149584). See p. 2010; Editorial, p. 2002 Clinical features and laboratory abnormalities of multifocal varicella-zoster virus (VZV) vasculopathy with temporal artery (TA) infection mimic giant cell arteritis (GCA). Immunohistochemistry revealed VZV antigen in 5/24 (21%) TAs from patients with clinically suspect, pathologically negative GCA. Identification of VZV vasculopathy …

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