Abstract
In 50 patients with drug-resistant epilepsy (DRE), external trigeminal nerve stimulation (eTNS) was associated with an improvement in responder rate at 18 weeks, resulting in improvements in mood. eTNS is a promising new therapy for DRE—it is noninvasive, well tolerated, and may benefit depression, a major comorbidity in epilepsy. See p. 786 From editorialists Faught & Tatum: “Although we do not know the best electrical pathway to the brain for seizure control, the trigeminal nerve, as the largest cranial nerve, is a sort of superhighway.” …
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