Abstract
#### Notable in Neurology This Week This issue features an article that investigates the clinical effect of renal impairment on intracerebral hemorrhage; another examines neuroanatomical signatures of MAPT mutation carriers to determine whether there are distinct groups. A featured Review compares 2 long-read sequencing technologies and discusses how they can be applied to neurodegenerative diseases. ### Effects of High- and Low-Efficacy Therapy in Secondary Progressive Multiple Sclerosis ![Graphic][1]</img> This study compares the clinical effectiveness of high- and low-efficacy treatments for patients with secondary progressive multiple sclerosis (SPMS). Accounting for therapeutic lag, researchers found … [1]: /embed/inline-graphic-1.gif
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