Abstract

Eighty-three individuals with insidious onset/progressive dementia, clinically diagnosed with Alzheimer disease or small vessel vascular dementia, completed several neuropsychological measures. These data underscore the need to better understand the threshold at which leukoaraiosis affects and alters the phenotypic expression in insidious onset dementia syndromes. Two other papers this week also discuss the topic of white matter changes and cognitive impairment. See p. 734, see also pp. 741 and 748 From editorialists Carmichael & Salloway: “Should early white matter …

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