Spontaneous Tumor Lysis Syndrome in Myeloproliferative Disorder: A Rarely Reported Clinical Entity

Abstract

Tumor lysis syndrome (TLS) is an oncologic emergency resulting from a massive breakdown of tumor cells. It causes electrolyte imbalance and acute renal failure. It occurs after the initiation of chemotherapy. Spontaneous tumor lysis syndrome is seen in Burkitt's lymphoma, acute lymphoid leukemia, diffuse large B-cell lymphoma, and solid tumors like breast and prostate cancer. Spontaneous tumor lysis syndrome is exceedingly rare in patients with myeloproliferative disorders. We report a rare case of spontaneous tumor lysis in an 82-year-old female patient with a myeloproliferative disorder.