Abstract

Daily amygdaloid stimulation administered to rats at current levels initially too low to produce a motor response but high enough to produce an electrographic afterdischarge (AD) resulted in the progressive development and intensification of stimulus-induced epileptic activity (kindling). In contrsst to previous studies, however, stimulation was continued long after the point where the exacerbation of motor seizures (MSs) seemed complete. Several animals were stimulated for up to 7 months and, with continued stimulation, an epileptic syndrome characterized by spontaneous motor seizures was observed to develop.

Talk to us

Join us for a 30 min session where you can share your feedback and ask us any queries you have

Schedule a call

Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.