Spontaneous Resolution of Retinal Pigment Epithelial Detachments and Visual Improvement in Patient with MPGN II: A Case Report

T Empeslidis,U Imrani,S Banerjee,A Vardarinos,N Menassa

doi:10.1155/2012/864198

Abstract

A 31-year-old female suffering from membranoproliferative glomerulonephritis type II (MPGN II) presented to the Eye Casualty Department reporting a history of blurred and distorted vision. The patient appeared to have drusenoid retinal epithelial detachments and minimal intraretinal fluid. The subretinal deposits, basal lamina drusen, and pigment epithelial detachment appeared to resemble a “stars in the sky” picture with no symmetry between the eyes. The retinal pigment epithelial detachments improved and flattened over 18 month. and the best corrected visual acuity improved in the most affected eye. There was no evidence of neovascularization, and the intraretinal fluid disappeared spontaneously.

Highlights

We present a case of a 31-year-old female who attended our Eye Casualty Department reporting a 2-month history of blurred and distorted vision
membranoproliferative glomerulonephritis type II (MPGN II) or dense deposit disease is a rare condition that can potentially affect the eyes and the ocular manifestations were first described by Duvall-Young et al in 1989 [1]
It is the causative factor of deposition of electron dense material within the kidney’s glomerular membrane and within the Bruch’s membrane and the retinal pigment epithelium (RPE) choriocapillaris area [1, 2]

Summary

Introduction

We present a case of a 31-year-old female who attended our Eye Casualty Department reporting a 2-month history of blurred and distorted vision. This resulted in problems with near vision tasks such as reading and working on the laptop. The patient had her medical and ocular history taken, revealing a long standing history of membranoproliferative glomerulonephritis type II (MPGN II) which had been confirmed with renal biopsy. Blood tests including full blood count, urea, and electrolytes and liver function tests were performed in addition to ocular coherence tomography (OCT) and fluorescein angiography (FFA)

Case Report

Discussion