Abstract
Systemic thrombolysis in the setting of acute myocardial infarction (AMI) remains an effective treatment. However, it exposes to a non-negligible bleeding risk Diffuse pulmonary hemorrhage is a of the rare complication of thrombolysis, it can cause a serious medical emergency potentially leading to fatal acute respiratory failure. We present four cases of diffuse pulmonary hemorrhage following administration of intravenous thrombolytic therapy (Tenecteplase), the Lack of recognition that the lungs too may be a site of spontaneous hemorrhage during thrombolytic therapy may lead to a considerable diagnostic and therapeutic delay. Pulmonary hemorrhage should be considered in the differential diagnosis of patients who receive thrombolytic therapy in whom new roentgenographic pulmonary infiltrates present accompanied by decreases in hematocrit value.
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