Abstract
Red-bellied lemurs (Eulemur rubriventer: genus Eulemur, family Lemuridae, Suborder Strepsirrhini) are non-human primates endemic to the forests of Madagascar and listed as 'vulnerable' on the IUCN Red List of Threatened Species. Currently, descriptions of neoplasia in this species are extremely scarce, with only one case of hepatocellular adenoma reported. Prosimian submissions received by the Anatomic Pathology Service at North Carolina State University from January 2010 to January 2021 were retrieved. A total of 200 cases of Strepsirrhini prosimians were identified, representing 57 (28.5%) individuals from the genus Eulemur of which seven (12.3%) cases were red-bellied lemurs. Neoplasia was identified in two of the seven (28.57%) cases. The first case was a 25-year-old, intact female with hepatocellular carcinoma and the second a 33-year-old, intact female with a cervical mass consistent with osteoblastic osteosarcoma arising from the left clavicular bone. Hepatocellular neoplasms are commonly reported in prosimians, with carcinomas more frequent than adenomas. In contrast, osteosarcoma has been rarely described in lemuriformes, with four cases reported. To our knowledge, this is the first report of osteosarcoma and hepatocellular carcinoma in a red-bellied lemur.
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