Abstract
IntroductionBiomechanical changes in the cornea during pregnancy might lead to pathological conditions such as corneal perforation or melting.Case presentationA 33-year-old Asian female who underwent penetrating keratoplasty in both eyes developed corneal melting in the right eye and marginal keratitis in the left eye in her fifth month of pregnancy. Marginal keratitis in the left eye immediately subsided with topical steroid therapy. However, spontaneous corneal melting progressed in the right eye, despite oral steroid therapy and amniotic membrane transplantation. We performed tectonic penetrating keratoplasty and corneoscleral grafting in the right eye.ConclusionWe advise caution in the ophthalmologic care of pregnant patients who have preexisting corneal thinning disorders or who have undergone multiple corneal surgeries, because physiologic changes during pregnancy might contribute to corneal changes leading to spontaneous melting especially in patients with compromised cornea.
Highlights
Several case reports have demonstrated that biomechanical changes in the cornea during pregnancy might lead to pathological conditions such as corneal perforation or melting [2,3]
We report a case of a woman who developed spontaneous corneal melting which started in her fifth month of pregnancy, and required tectonic corneal grafting
Our patient was in her fifth month of pregnancy when she developed transient marginal keratitis in one eye and spontaneous corneal melting in the other eye, which progressed to the point that it required a tectonic corneal graft
Summary
We advise caution in the ophthalmologic care of pregnant patients who have preexisting corneal thinning disorders or who have undergone multiple corneal surgeries, because physiologic changes during pregnancy might contribute to corneal changes leading to spontaneous melting especially in patients with compromised cornea
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