Abstract
A study of spontaneous contractility of human myometrium in an isolated isometric system has indicated that well defined differences are found between myometrial specimens excised during the proliferative phase of the menstrual cycle and those associated with a secretory endometrium. Preparations from the gravid uterus exhibited characteristics that differentiate them from specimens excised from nonpregnant uteri. In subjects with functioning endometria, age and parity had no demonstrable influence upon rate of contraction or maximum tension of the preparations. Lowering of environmental temperature resulted in a marked reduction in spontaneous contraction rate and a prolongation of the contraction cycle but without a reduction in maximum tension developed during contraction cycles.
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